{"id":"4b8a8d68-7287-5891-a721-01d177ccc691","edition":"sk","language":"sk","version":2,"url":"https://novinky.nakupovanie.sk/clanok/4b8a8d68-7287-5891-a721-01d177ccc691","title":"Mozgový okruh u samcov myší ovplyvňuje tlmenie bolesti pri strachu","summary":"Pokusy na samcoch myší ukázali, že bunky produkujúce somatostatín v určitej oblasti stredného mozgu regulujú analgéziu vyvolanú obrannými stavmi.","paragraphs":["Vedci skúmali bunky produkujúce somatostatín vo ventrolaterálnej periakveduktálnej sivej hmote stredného mozgu. Kombinovali behaviorálne, anatomické, optogenetické a elektrofyziologické metódy, pričom experimenty uskutočnili na samcoch myší.","Optogenetické utlmenie týchto buniek podporilo analgéziu bez ohľadu na obranný stav zvieraťa. Naopak, aktivovanie buniek s dlhými výbežkami smerujúcimi do rostrálnej ventromediálnej miechy zrušilo analgéziu spojenú so správaním vyvolaným strachom.","Výsledky podľa autorov poukazujú na nervový okruh, ktorý reguluje potlačenie bolesti počas obranných stavov. Zistenia sú obmedzené na pokusy so samcami myší.","Štúdiu „Midbrain somatostatin-expressing cells control pain-suppression during defensive states“ zverejnil 10. novembra 2026 časopis eLife. Autormi sú Nanci Winke, Frank Aby, Daniel Jercog, Coline Riffault, Rabia Bouali-Benazzouz, Juliette Viellard, Delphine Girard, Zoe Grivet, Marc Landry, Laia Castell, Emmanuel Valjent, Stephane Valerio, Pascal Fossat a Cyril Herry. Toto je pôvodné slovenské spracovanie abstraktu vydaného pod licenciou CC BY 4.0."],"topic":"science","category":"nature-animals","publishedAt":"2026-11-10T09:06:25.585Z","updatedAt":"2026-11-10T09:06:25.585Z","sources":[{"id":"elife-open-research:elife-doi:10.7554.eLife.106826","url":"https://elifesciences.org/articles/106826","publisher":"eLife","observedAt":"2026-11-10T09:04:17.269Z","attribution":{"credit":"Nanci Winke; Frank Aby; Daniel Jercog; Coline Riffault; Rabia Bouali-Benazzouz; Juliette Viellard; Delphine Girard; Zoe Grivet; Marc Landry; Laia Castell; Emmanuel Valjent; Stephane Valerio; Pascal Fossat; Cyril Herry","title":"Midbrain somatostatin-expressing cells control pain-suppression during defensive states","license":"Creative Commons Attribution 4.0 International (CC BY 4.0)","licenseURL":"https://creativecommons.org/licenses/by/4.0/","rightsNotice":"Source: eLife. This article is explicitly marked CC BY 4.0. Credit the original title, all listed authors and article URL; link the licence and identify translation or adaptation. Only the article abstract is used here. Figures, photos, logos and third-party material are excluded unless separately licensed. No eLife endorsement or separate model-training grant is asserted.","changeNotice":"AI-assisted original local-language article; source claims require the original editorial verification.","proofURL":"https://elifesciences.org/terms"}}],"assets":[{"url":"https://novinky.nakupovanie.sk/media/9504c6562b7beacd818f8c1cf576351c5d3624ef8f8b9cc1e6373a9ccbe5f93c.jpg","kind":"image","credit":"Vlastná redakcia","reuse":"allowed","redistribution":"allowed","alt":"AI ilustrácia k téme článku","caption":"AI ilustrácia; nezobrazuje skutočnú udalosť ani výsledok štúdie.","sourceURL":"https://novinky.nakupovanie.sk/media/9504c6562b7beacd818f8c1cf576351c5d3624ef8f8b9cc1e6373a9ccbe5f93c.jpg","licenseProofURL":"https://novinky.nakupovanie.sk/o-projekte#obrazky","license":"Vlastná AI ilustrácia; ďalšie použitie s uvedením zdroja","aiGenerated":true}],"image":{"url":"https://novinky.nakupovanie.sk/media/9504c6562b7beacd818f8c1cf576351c5d3624ef8f8b9cc1e6373a9ccbe5f93c.jpg","alt":"AI ilustrácia k téme článku","caption":"AI ilustrácia; nezobrazuje skutočnú udalosť ani výsledok štúdie.","credit":"Vlastná redakcia","sourceURL":"https://novinky.nakupovanie.sk/media/9504c6562b7beacd818f8c1cf576351c5d3624ef8f8b9cc1e6373a9ccbe5f93c.jpg","license":"Vlastná AI ilustrácia; ďalšie použitie s uvedením zdroja","licenseProofURL":"https://novinky.nakupovanie.sk/o-projekte#obrazky","aiGenerated":true,"illustration":true,"redistribution":"allowed"},"generatedWithAI":true,"textRights":{"status":"allowed","grant":"novinky-text-reuse-v1","termsURL":"https://novinky.nakupovanie.sk/pre-ai#novinky-text-reuse-v1","basis":"original_from_facts","scope":"own_original_wording_in_title_summary_paragraphs","attribution":{"publisher":"novinky.nakupovanie.sk","canonicalURL":"https://novinky.nakupovanie.sk/clanok/4b8a8d68-7287-5891-a721-01d177ccc691","edition":"sk","language":"sk","version":2},"allowedUses":["read","machine_process","quote","summarize","translate","adapt","republish"],"conditions":["credit_and_link","identify_changes","retain_source_credits","follow_corrections_and_withdrawals"],"excludes":["third_party_wording_and_quotations","images_audio_video","third_party_tables_and_graphics","trademarks_and_personality_rights"],"modelTraining":"not_granted_by_this_permission"},"corrections":[],"correctionsWindow":"latest20"}